Песнь клетки. Медицинские исследования и новый человек - Сиддхартха Мукерджи

15 Sornberger J. Dreams and Due Diligence.

16 Там же.

17 Там же.

18 Из беседы с Ирвингом Вейссманом в 2019 году.

19 Spangrude G. J. et al. Purification and Characterization of Mouse Hematopoietic Stem Cells. Science 241, no. 4861 (1988): 58–62; cm. также: Ema H. et al. Quantification of Self-Renewal Capacity in Single Hematopoietic Stem Cells from Normal and Lnk-Deficient Mice. Developmental Cell 8, no. 6 (2006): 907-14.

20 Spangrude G.J. et al. Purification and Characterization of Mouse Hematopoietic Stem Cells; см. также: Baum С. M. et al. Isolation of a Candidate Human Hematopoietic Stem-Cell Population. PNAS 89, no. 7 (1992): 2804-8; Peault B. et al. Analysis of Candidate Human Blood Stem Cells in “Humanized” Immune-Deficiency SCID Mice. Leukemia 7, suppl. 2 (1993): S98-101.

21 Robinson W et al. Stimulation by Normal and Leukemic Mouse Sera of Colony Formation in Vitro by Mouse Bone Marrow Cells. Journal of Cellular Therapy 69, no. 1 (1967): 83–91; см. также: Stanley E. R., Metcalf D. Partial Purification and Some Properties of the Factor in Normal and Leukaemic Human Urine Stimulating Mouse Bone Marrow Colony Growth in Vitro. Australian Journal of Experimental Biology and Medical Science 47, no. 4 (1969): 467-83.

22 Madren C. First Successful Bone Marrow Transplant Patient Surviving and Thriving at 60. AAAS, 2014; см. также: Mukherjee S. The Promise and Price of Cellular Therapies. New Yorker, 2019.

23 Appelbaum F. R. Edward Donnall Thomas (1920–2012). The Hematologist 10, no. 1 (2013).

24 Henig I., Zuckerman T. Hematopoietic Stem Cell Transplantation – 30 Years of Evolution and Future Perspectives. Rambam Mai-monides Medical Journal 5, no. 4 (2014).

25 Watts G. Georges Mathe. Lancet 376, no. 9753 (2010): 1640; см. также: Martin Id. Dr. Georges Mathe, Transplant Pioneer, Dies at 88. New York Times, 2010.

26 Doughton S.Dr. Alex Fefer, 72, Whose Research Led to First Cancer Vaccine, Dies. Seattle Times, 2010; см. также: Campanario G. At 79, Noted Scientist Still Rows to Work and for Play. Seattle Times, 2014; Keown S. Inspiring a New Generation of Researchers: Beverly Torok-Storb, Transplant Biologist and Mentor. Fred Hutchinson Cancer Research Center, 2014.

27 Mielcarek M. et al. CD34 Cell Dose and Chronic Graft-Versus-Host Disease after Human Leukocyte Antigen-Matched Sibling Hematopoietic Stem Cell Transplantation. Leukemia Lymphoma 45, no. 1 (2004): 27–34.

28 Appelbaum F. R. Haematopoietic Cell Transplantation as Immunotherapy. Nature 411 (2001): 385-9.

29 Из беседы с Фредериком Аппельбаумом в июне 2019 года.

30 Anatoly Grishchenko, Pilot at Chernobyl, 33. New York Times, 1990; см. также: Klass T Chernobyl Helicopter Pilot Getting Bone-Marrow Transplant in Seattle. AP News, 1990.

31 Shim oni A. et al. Long-Term Survival and Late Events after Allogeneic Stem Cell Transplantation from HLA-Matched Siblings for Acute Myeloid Leukemia with Myeloablative Compared to Reduced-Intensity Conditioning. Journal of Hematology & Oncology 9 (2016); см. также: Acute Myeloid Leukemia (AML) – Adult. Disease-Specific Indications and Outcomes. National Marrow Donor Program.

32 Kolata G. Man Who Helped Start Stem Cell War May End It. New York Times, 2007.

33 Thomson J. A. et al. Embryonic Stem Cell Lines Derived from Human Blastocysts. Science 282, no. 5391 (1998): 1145-7.

34 Cyrano ski D. How Human Embryonic Stem Cells Sparked a Revolution. Nature, 2018.

35 Murugan V. Embryonic Stem Cell Research: A Decade of Debate from Bush to Obama. Yale Journal of Biology and Medicine 82, no. 3 (2009): 101-3.

36 Takahashi K., Yamanaka S. Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors. Cell 126, no. 4 (2006): 663-76; см. также: Yamanaka S. The Winding Road to Pluripotency. Nobel Lecture, Stockholm, December 7, 2012.

37 Scudellari M. A Decade of iPS Cells. Nature 534 (2016): 310-2.

38 Evans M. J., Kaufman M. H. Establishment in Culture of Pluripotential Cells from Mouse Embryos. Nature 292 (1981): 154-6.

39 Takahashi K. et al. Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors. Cell 131, no. 5 (2007): 861-72.

Восстанавливающие клетки. Повреждения, распад и постоянство

1 Ryan К. Tenderness and Rot // The Best of It.

2 Service R. Bonehead Bill. Canadian Poets, Best Poems Encyclopedia.

3 Worthley D. L. et al. Gremlin 1 Identifies a Skeletal Stem Cell with Bone, Cartilage, and Reticular Stromal Potential. Cell 160, no. 1–2 (2015): 269-84.

4 Chan С. K. F. et al. Identification of the Human Skeletal Stem Cell. Cell 175, no. 1 (2018): 43–56.e2i.

5 Zhou B. O. et al. Leptin-Receptor-Expressing Mesenchymal Stromal Cells Represent the Main Source of Bone Formed by Adult Bone Marrow. Stem Cell 15, no. 2 (2014): 154-68.

6 Folsing A. Albert Einstein: A Biography. New York: Penguin Books, 1998.

7 Larkin P. The Old Fools, High Windows. London: Faber & Faber, 2012.

Эгоистичные клетки. Экологическое равновесие и рак

1 Woglom W. Н. General Review of Cancer Therapy, Approaches to Tumor Chemotherapy. Washington, DC: American Association for the Advancement of Sciences, 1947. Общая информация о раке: De-

Vita V et al. Cancer: Principles & Practice of Oncology. Philadelphia: Lippincott Williams & Wilkins, 2012; см. также: Mukherjee S.

The Emperor of All Maladies: A Biography of Cancer. London: Harper Collins, 2011. О мутациях генов-драйверов и генов-пассажиров: Anderson К. et al. Genetic Variegation of Clonal Architecture and Propagating Cells in Leukaemia. Nature 469 (2011): 356-61; And or N. et al. PanCancer Analysis of the Extent and Consequences of Intratumor Heterogeneity. Nature Medicine 22 (2016): 105-13;

Vandin F. Computational Methods for Characterizing Cancer Mutational Heterogeneity. Frontiers in Genetics 8, no. 83 (2017).

2 Krivstov A. V et al. Transformation from Committed Progenitor to Leukaemia Stem Cell Initiated by MLL-AF9. Nature 442, no. 7104 (2006): 818-22.

3 Bachoo R. M. et al. Epidermal Growth Factor Receptor and Ink4a/Arf. Cancer Cell 1, no. 3 (2002): 269-77; Holland E. C. Gliomagenesis: Genetic Alterations and Mouse Models. Nature Reviews Genetics 2, no. 2 (2001): 120-9.

4 Dick J. E., Lapid от T. Biology of Normal and Acute Myeloid Leukemia Stem Cells. International Journal of